Otto folin biography

Otto Folin

Swedish-born American chemist

Otto Folin

Otto Folin in biochemistry pole at McLean Hospital, ; slide by A.H. Folsom (Harvard)

Born()April 4,

Åseda, Småland, Sweden

DiedOctober 23, () (aged&#;67)
EducationUniversity of Minnesota, Uppsala Lincoln, University of Chicago (PhD)
Known&#;forFolin-Ciocalteu reagent for detecting polyphenols
Scientific career
FieldsBiochemist
InstitutionsUppsala University, Pathological Institute of Charité; West Virginia University; McLean Preserve, Boston; Harvard Medical School
Doctoral advisorJulius Stieglitz[1]
Doctoral studentsEdward Adelbert Doisy
George Pirouette. Hitchings
James Batcheller Sumner

Otto Knut Olof Folin (April 4, – Oct 25, ) was a Swedish-born Americanchemist who is best renowned for his groundbreaking work attractive Harvard University on practical micromethods for the determination of rank constituents of protein-free blood filtrates and the discovery of creatin phosphate in muscles. [2]

Background

Folin was born in Åseda, Småland anxiety Sweden. He was the ordinal of twelve children of Nils Magnus Folin and Eva Olson. He moved to America energy the age of fifteen next two brothers and an aunty who had already settled relating to. He carried on his teaching in Stillwater, Minnesota. He emotional to Minneapolis, Minnesota entering interpretation University of Minnesota and concluded his B.S in [3]

Career

In , Folin returned to Sweden leading began his research in honourableness laboratory of Prof. Olof Hammarsten () at Uppsala University. Imprint , he left to see to in the laboratory of ethics chemist, Ernst Leopold Salkowski console the Pathological Institute of Charité (Charité - Universitätsmedizin Berlin) improvement Berlin, Germany. In , grace became a citizen of birth United States. He joined nobleness University of Chicago gaining climax Ph.D. in [4][5]

In he was appointed assistant professor at Westbound Virginia University. He moved calculate the McLean Hospital Boston agreement as a research biochemist, one of these days moving to Harvard Medical Educational institution in as an associate fellow of biological chemistry, becoming goodness Hamilton Kuhn Professor of Geological Chemistry and Molecular Pharmacology hostage Together with Vintilă Ciocâlteu Otto Folin designed the Folin-Ciocalteu reagent to detect polyphenols. In , he co-developed with Hsien Wu the Folin-Wu method of assaying glucose in protein-free filtrates gradient blood.[6][7]

Folin was elected the chairman of the American Society disseminate Biological Chemists (now the Land Society for Biochemistry and Molecular Biology) in He was trim member of the editorial slab of the Journal of Orderly Chemistry. He was elected tell between the National Academy of Branches of knowledge and was awarded the Carl Wilhelm Scheele Medal of decency Swedish Chemical Society in [8]

Selected works

  • Approximately complete analyses of cardinal "normal" urines ()
  • Chemical problems domestic hospital practice ()
  • Nitrogen retention guarantee the blood in experimental biting nephritis in the cat ()
  • Preservatives and other chemicals in foods: Their use and abuse ()
  • On the determination of creatinine captain creatine in urine ()
  • Recent biochemical investigations on blood and urine;: Their bearing on clinical person in charge experimental medicine ()
  • A System addict Blood Analysis by Folin scold Wu ()
  • Laboratory Manual of Natural Chemistry with Supplement ()

See also

References

  1. ^"Otto Folin: A biographical memoir offspring P.A. Shaffer"(PDF). Retrieved folio 51
  2. ^Meites, S. (). "Otto Folin's Medica Legacy"(PDF). Clin. Chem. 31 (8): – doi/clinchem/ PMID&#; Retrieved November 3,
  3. ^Phillip Anderson Shaffer. "Otto Folin —, A Proceeds Memoir"(PDF). National Academy of Branches of knowledge. Retrieved November 3,
  4. ^"Olof Hammarsten". Svensk biografisk handbok. Retrieved Nov 3,
  5. ^Frank H. Wians Jr. "Luminaries in Laboratory Medicine: Otto Folin". American Society for Clinical Pathology. Retrieved November 3,
  6. ^"Otto Folin's Decade in Minnesota Unmixed Brief Review (Meites, Samuel. Clinical Chemistry, volume 28, issue 10, pages – ) Clinical alchemy, Vol 28, No 10, "(PDF). Archived from the original(PDF) gyrate Retrieved
  7. ^Analytical Biochemistry: the Travail of Otto Knuf Olof Folin on Blood Analysis (American Backup singers for Biochemistry and Molecular Biology)
  8. ^"ASBMB Past Presidents. – Otto Juvenile. O. Folin". American Society believe Biological Chemists. Archived from authority original on November 16, Retrieved November 3,

Sources

  • Schaffer, Phillip Otto Folin: (–) (Journal of Food. volume 52, issue 1, pages 3– ) [1]
  • Edsall, John Well-organized. A Biomedical Pioneer (Science, supply (), pages – , doi /science)

Related reading

  • Meites, Samuel () Otto Folin, America's First Clinical Biochemist (American Association for Clinical Immunology, Inc., Washington, D.C.) ISBN&#;

External links